Cerebrovascular accident
|
0.590 |
GeneticVariation
|
group |
LHGDN |
Association of human platelet alloantigen 1 through 5 polymorphisms with ischemic stroke.
|
18057877 |
2008 |
Cerebrovascular accident
|
0.590 |
GeneticVariation
|
group |
LHGDN |
Previous studies showed an association between the GPIIIa Pl(A1/A2) polymorphism and coronary thrombosis, while there is only contrasting evidence about its role in stroke.
|
17278970 |
2007 |
Cerebrovascular accident
|
0.590 |
GeneticVariation
|
group |
LHGDN |
PLA1/A2 polymorphism of the platelet glycoprotein receptor IIb/IIIa in young patients with cryptogenic TIA or ischemic stroke.
|
12586134 |
2002 |
Cerebrovascular accident
|
0.590 |
Biomarker
|
group |
RGD |
Analysis of combined treatment of embolic stroke in rat with r-tPA and a GPIIb/IIIa inhibitor.
|
15678115 |
2005 |
Cerebrovascular accident
|
0.590 |
GeneticVariation
|
group |
BEFREE |
A common isoform of integrin β3, Leu33Pro is associated with enhanced platelet function and increased risk for coronary thrombosis and stroke, although these findings remain controversial.
|
24695082 |
2014 |
Cerebrovascular accident
|
0.590 |
GeneticVariation
|
group |
BEFREE |
We used a population-based case-control design to examine the association of the GpIIIa polymorphism P1A2 with stroke in young women.
|
9506596 |
1998 |
Cerebrovascular accident
|
0.590 |
GeneticVariation
|
group |
BEFREE |
Previous studies showed an association between the GPIIIa Pl(A1/A2) polymorphism and coronary thrombosis, while there is only contrasting evidence about its role in stroke.
|
17278970 |
2007 |
Cerebrovascular accident
|
0.590 |
GeneticVariation
|
group |
LHGDN |
In contrast to females with LVD stroke, we found that males with LVD stroke presented with an overrepresentation of at least 1 A2 allele of the GpIIIa gene when compared with their controls (39.7% versus 23.0%; P=0.003).
|
15178823 |
2004 |
Cerebrovascular accident
|
0.590 |
GeneticVariation
|
group |
BEFREE |
We investigated the association of the GpIIb/IIIa complex gene polymorphism with stroke risk in 306 patients with acute ischemic stroke and 266 control subjects by determining the GpIIb and GpIIIa genotype from leukocyte DNA by polymerase chain reaction (PCR) followed by FokI and ScrFI digestion, respectively.
|
22207115 |
2012 |
Cerebrovascular accident
|
0.590 |
GeneticVariation
|
group |
BEFREE |
We then assessed the relation of allelic variants of genes modulating clopidogrel absorption (ABCB1), metabolic activation (CYP3A5 and CYP2C19), and biologic activity (P2RY12 and ITGB3) to the risk of death from any cause, nonfatal stroke, or myocardial infarction during 1 year of follow-up.
|
19106083 |
2009 |
Cerebrovascular accident
|
0.590 |
GeneticVariation
|
group |
BEFREE |
The genotype distribution of the GpIIIa gene in patients with LVD stroke (A1/A1, 63%; A1/A2, 34.8%; A2/A2, 2.2%) differed significantly from their controls (A1A1, 79.3%; A1/A2, 20.1%; A2/A2, 0.6%).
|
15178823 |
2004 |
Cerebrovascular accident
|
0.590 |
Biomarker
|
group |
BEFREE |
Positive associations between total number of pMVs, AnV+ MVs and AnV+/CD61+ MVs and atherosclerotic thickening of carotid intima-media in stroke patients were found.
|
30763823 |
2019 |
Cerebrovascular accident
|
0.590 |
Biomarker
|
group |
CTD_human |
Depressed platelet status in an elderly patient with hemorrhagic stroke after thrombolysis for acute myocardial infarction. GUSTO-III Investigators.
|
9445356 |
1998 |
Prostatic Neoplasms
|
0.360 |
Biomarker
|
group |
LHGDN |
Inhibition of alpha(v)beta3 integrin reduces angiogenesis, bone turnover, and tumor cell proliferation in experimental prostate cancer bone metastases.
|
14524530 |
2003 |
Prostatic Neoplasms
|
0.360 |
Biomarker
|
group |
LHGDN |
Osteoblasts-derived BMP-2 enhances the motility of prostate cancer cells via activation of integrins.
|
18512729 |
2008 |
Prostatic Neoplasms
|
0.360 |
AlteredExpression
|
group |
LHGDN |
Expression and activation of alpha v beta 3 integrins by SDF-1/CXC12 increases the aggressiveness of prostate cancer cells.
|
17034033 |
2007 |
Prostatic Neoplasms
|
0.360 |
AlteredExpression
|
group |
LHGDN |
Alpha(v)beta3 integrin expression up-regulates cdc2, which modulates cell migration.
|
12771130 |
2003 |
Prostatic Neoplasms
|
0.360 |
Biomarker
|
group |
CTD_human |
[Prognostic implications of GP3a glucoprotein gene PLA1/PLA2 allele in prostatic cancer: pilot results of the study].
|
16158739 |
2005 |
Prostatic Neoplasms
|
0.360 |
AlteredExpression
|
group |
LHGDN |
Role of the orphan nuclear receptor ROR alpha in the control of the metastatic behavior of androgen-independent prostate cancer cells.
|
12168086 |
2003 |
Prostatic Neoplasms
|
0.360 |
AlteredExpression
|
group |
LHGDN |
Prostate cancer specific integrin alphavbeta3 modulates bone metastatic growth and tissue remodeling.
|
17369840 |
2007 |
Arterial Occlusive Diseases
|
0.200 |
Biomarker
|
group |
RGD |
Inhibition of the intimal hyperplasia in an arterial autograft model by blockade of the N-terminal of the integrin beta3 subunit by monoclonal antibody P37.
|
16793666 |
1997 |
Pneumonia, Bacterial
|
0.200 |
Biomarker
|
group |
RGD |
Expression of integrin subunits alphav and beta3 in acute lung inflammation.
|
15114484 |
2004 |
Other primary thrombocytopenia
|
0.200 |
Biomarker
|
group |
MGD |
Beta3-integrin-deficient mice are a model for Glanzmann thrombasthenia showing placental defects and reduced survival.
|
9916135 |
1999 |
Other primary thrombocytopenia
|
0.200 |
Biomarker
|
group |
MGD |
Enhanced pathological angiogenesis in mice lacking beta3 integrin or beta3 and beta5 integrins.
|
11786903 |
2002 |
Other primary thrombocytopenia
|
0.200 |
Biomarker
|
group |
MGD |
Beta3 integrin deficiency promotes cardiac hypertrophy and inflammation.
|
17184791 |
2007 |